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Buy PEG-MGF (Pegylated Mechano Growth Factor) Online from our online store. Buy PEG-MGF online at best price. PEG-MGF research peptide.
1.What is PEG-MGF (Pegylated Mechano Growth Factor)?
PEG-MGF (Pegylated Mechano Growth Factor) is a variant of IGF-1 (Insulin-like Growth Factor) which leads to an increase in the muscle cells necessary for adult muscles to continue growth beyond their genetic limit. Like other forms of IGF-1, PEG-MGF (also known as IGF-1ec) creates new muscle cells and stimulates muscle growth by promoting nitrogen retention and increasing protein synthesis.PEG-MGF differs from regular MGF as it has undergone a process of “Pegylation†which extends its half-life from less than 30 minutes to several days.

Product Name:Peg-MGF
Catalogue Number:L463678
Synonyms:PEG-MGF,Mechano growth factor,IGF-1 EC
CAS NO. : 616204-22-9
Molecular Formula:C121H200N42039
Molecular Weight:2948.15+
Source:Chemical Synthesis

2. Pegylated Mechano Growth Factor (PEG-MGF) dosage:
The average dose is 500 mcg per 24 hours; the frequency is 2-3 times per week. The drug is injected subcutaneously 1-2 hours before training to imitate physiologic secretion. The cycle duration is 5-6 weeks.

3.NOTE for Pegylated Mechano Growth Factor (PEG-MGF):
Do not mix up all your vials at once. You should only mix up 1 (one) vial at a time and leave the rest in powder form until you are ready to use the next vial.
Running PEG-MGF in synergy with IGF is perfect but there are things you need to know.If you dose them at the same time, as IGF has such strong receptor affinity, The effectivness of MGF will just be wasted.The best option and the very best choice i feel is this....IGF DES on workout days Pre workout, or IGF1-LR3 this wont blunt your bodys own MGF release from the liver, and whereas IGF1-LR3 has a more systematic effect and only a very small localised anabolic effect, DES on the other hand is verty anabolic in a localised way, so bring up lagging muscle parts with DES, and then the following day Dose MGF at 200-400mcg subq to increase recovery and the mechanism for growth. Perfect synergy.Over a 4 week run i noticed about 4lb increase with the PEG-MGF and DES partnership. And roughly the same weight in fat loss, very impressive, some though have noted far greater increases in muscle mass.If your on an AAS cycle there is no need for the addition of DES as IGF levels will already be elevated, then the addition of PEG MGF can take your recovery and gains to a new level.


4. HOW TO USE Pegylated Mechano Growth Factor (PEG-MGF)
This is a very important section.When using MGF thats pegylated thats the addition of Polyethylene glycol, its a non toxic additive that increased the half life of MGF from minutes to hours.This means its uses and versatility make it a tremendous addition to a bodybuilders aresnal.I have found it most effective as its effects are systematic, that means they have a whole body effect wherever muscle has been damaged or is diseased. The next aspect we need to look at is how to make the most use of a long acting version of MGF.When your muscle is damaged your body releases a pulse of an MGF splice variant as i outlined above, followed by a less anabolic longer acting version from the liver... So it seems a waste to inject MGF at this time as you will just blunt your bodys own release, your not enhaning it.So using PEG-MGF on non workout days is actualy the very best route, the muscle has been damaged, so there are plenty of receptors for MGF, the effects are systematic so all muscles will be helped to recover through increased nitrogen retention, protein turnover, and satelite cell activation. Recovery is just going to sky rocket.Doing this means your increasing the length of your bodys own mechanism for muscle repair and growth, your opening up the anabolic window.

5. Why PEGylated MGF is better
MGF exhibits local effects in skeletal muscle and without modification is not systemic(can't travel through the body). The problem with synthetic MGF is that it is introduced IM and is water based so it goes into the blood stream. MGF is not stable in the blood stream for more than a matter of minutes. Biologically produced MGF is made locally and does not enter the bloodstream and is short acting so stability is not an issue. By PEGylating the MGF we can make synthetic MGF injected IM almost as efficient as local produced MGF. Clinically proven Advanced Pegylation, the technology of polyethylene glycol (PEG) conjugation, holds significant promise in maintaining effective plasma concentrations of systemically administered drugs. It does this by surrounding part of the peptide with a unique structure made of polyethylene glycol,which can be attached to a protein molecule. The result of a correct PEGylation is simlarto the protective mechanism of a turtle shell. The polyethylene glycol groups protect the peptide but don't surround it completely. The active sites of the peptide are still free to do their biological function. In this case the shell is a negative charged shield against positively charged compounds that would affect the protein. This also provides a nice steric chamber for the peptide to reside in. So it's a happy turtle.Neurological research has shown that utilizing PEGylated MGF resulted in a longer more stable acting version of the MGF peptide in serum/blood.

Bottom line
PEGylation can improve performance and dosing convenience of peptides, proteins,antibodies, oligonucleotides and many small molecules by optimizing pharmacokinetics,increasing bioavailability, and decreasing immunogenicity and dosing frequency.PEGylation also can increase therapeutic efficacy by enabling increased drug concentration, improved biodistribution, and longer dwell time at the site of action. As a result, therapeutic drug concentrations can be achieved with less frequent dosing'a significant benefit to patients who are taking injected drugs.

The PEG itself does not react in the body and is very safe. PEG has been approved by the US Food and Drug Administration (FDA) as a base or vehicle for use in foods and cosmetics and in injectable, topical, rectal and nasal pharmaceutical formulations. PEG has demonstrated little toxicity, is eliminated intact by the kidneys or in the feces and lacks immunogenicity. The risk associated with current PEGylated drugs are due to the way the drug itself acts not the PEG-MGF, as it is being currently sold, is getting a bad rep from people due to the fact they feel that they are not seeing gains from it. Many people believe that the use of MGF in their cycles or protocols just flat out won't work,however, this is far from the truth.Here it is plain and simple for you. Without any complex peptide understanding required other than the fact that PEGylation increases the stability, and lifetime of the peptide.MGF is responsible for increasing muscle stem cell count through a process called proliferation.As you see the effect going left to right here is exponential. The more stem cells you have the more that can be stimulated and replicated. In order to signal this replication there has to be sufficient saturation of cell receptors. Because attachment to a receptor is by simple probability, the more peptide and the more time the more probable a cell will reach saturation and begin to replicate.IF regular MGF has a shorter life span, it has a significantly smaller chance at saturating cells. It is not stable in the blood so its only real chance to bind is right at injection. If you calculate probability of binding via (time x concentration) and then PEG last appx 300 times longer, the probability of MGF having a significant effect is about 300 times at the same dosage. In other words you would need 300 times the regular MGF to bind to as many receptors as the PEGylated version. And even at that case the loss of peptide to the blood so fast would still limit the effects of MGF.Now you must also consider the cumulative effects of having longer term MGF action.AS you saw in the image, the number of receptors will increase, this increase the probability further for the PEG version so now every time you undergo muscle stem cell replication within the 4-8 days the PEG version is active you increase the probability proportional to the increase in cell number.So without knowing anything more than multiplication and the law of probability one can see that PEG-MGF is significantly more effective.

6. Storage for PEGylated Mechano Growth Factor (PEG-MGF):
Dilute in STERILE WATER OR STERILE ACETIC ACID ONLY 1ml or 2mls per vial.If dilluted with STERILE WATER this peptide must be used within 7 to 10 days!If diluted with ACETIC ACID this peptide must be used within 21 days!
Vials are freeze-dried and therefore will remain stable at room temperature for 1-2 months. However, for long term storage they should be kept a 2-8 degrees Celsius (refrigerator temperature), where they will remain stable for up to 18 months in powder form. Once mixed with mixing solution, vials should be stored in the refrigerator and not left at room temperature.

This product is NOT intended to prevent, treat, or cure disease conditions or to affect the structure or function of the body. The sale of this product is restricted to research applications ONLY. This product is NOT for human consumption. This product can be harmful if ingested. Picture may differ from actual product.

  • Model: PEG-MGF 2mg/vial
  • 2993 Units in Stock

Current Reviews: 74

This product was added to our catalog on Thursday 21 April, 2011.

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